#RADAR 10 HOMEOPATHIC FULL MANUAL#
#RADAR 10 HOMEOPATHIC FULL TRIAL#

Women are approximately twice as likely to develop MDD as men. MDD is associated with high health care costs. It is typically recurrent and often chronic. Major depressive disorder (MDD) is the fourth most disabling medical condition worldwide and it is expected to be ranked second by the year 2020.

#RADAR 10 HOMEOPATHIC FULL TRIAL#

Trial registrationД¬ Identifier: NCT01635218. It is an attempt to deal with the obstacles of homeopathic research due to the need for individual prescriptions in one of the most common psychiatric diseases. This study is the first trial of classical homeopathy that will evaluate the efficacy of homeopathic individualized treatment using C-potencies versus placebo or fluoxetine in peri- and postmenopausal women with moderate to severe depression. To determine differences in the primary and secondary outcomes among groups at baseline and weeks four and six, data will be analyzed by analysis of variance for independent measures with the Bonferroni post-hoc test. Efficacy data will be analyzed in the intention-to-treat population. Secondary outcomes are: Beck Depression Inventory change in mean score, GreeneвЂ™s Scale change in mean score, response and remission rates and safety. The primary outcome is change in the mean total score among groups on the 17-item Hamilton Rating Scale for Depression after the fourth and sixth week of treatment.

#RADAR 10 HOMEOPATHIC FULL MANUAL#

One hundred eighty nine peri- and postmenopausal women diagnosed with major depression according to the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (moderate to severe intensity) will be included. The study will be conducted in a public research hospital in Mexico City (JuГЎrez de MГ©xico Hospital) in the outpatient service of homeopathy. Methods/designДЄ randomized, placebo-controlled, double-blind, double-dummy, three-arm trial with a six-week follow-up study was designed. The aim of this study is to assess the efficacy and safety of the homeopathic individualized treatment versus placebo or fluoxetine in peri- and postmenopausal women with moderate to severe depression. In classical homeopathy, an individually selected homeopathic remedy is prescribed after a complete case history of the patient. Previous trials suggest that individualized homeopathic treatments improve depression. Use of homeopathy to treat depression is widespread but there is a lack of clinical trials about its efficacy in depression in peri- and postmenopausal women. The perimenopausal period refers to the interval when womenвЂ™s menstrual cycles become irregular and is characterized by an increased risk of depressive symptoms.

Radar 10 homeopathic full